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Gelatining Agent Hydroxypropyl Methylcellulose Excipient E5 For Tablet Coating

Gelatining Agent Hydroxypropyl Methylcellulose Excipient E5 For Tablet Coating

    • Gelatining Agent Hydroxypropyl Methylcellulose Excipient E5 For Tablet Coating
    • Gelatining Agent Hydroxypropyl Methylcellulose Excipient E5 For Tablet Coating
    • Gelatining Agent Hydroxypropyl Methylcellulose Excipient E5 For Tablet Coating
  • Gelatining Agent Hydroxypropyl Methylcellulose Excipient E5 For Tablet Coating

    Product Details:

    Place of Origin: CHINA
    Brand Name: RUNKEY
    Model Number: E3, E5, E6, E15, E30

    Payment & Shipping Terms:

    Minimum Order Quantity: 1DRUM, 25KG
    Price: Negotiation
    Packaging Details: 25KG/DRUM
    Payment Terms: L/C, T/T
    Supply Ability: 3000MT/YEAR
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    Detailed Product Description
    Product Name: HPMC Heavy Metal: 10ppm Max
    CAS No.: 9004-65-3 Residue On Ignition: 1.5% Max
    PH: 4.0 - 8.0 Standard: USP/BP/EP/CP
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    hpmc powder

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    pharmaceutical excipients

    White powder Gelatining agent HPMC E5 CAS 9004-65-3 for Tablet Coating

     

    Description:

    HPMC Hydroxy Propyl Methyl Cellulose is a kind of cold-water-soluble non-ionic polymer. It has different solubility, surface activity, gelatinization based on different methoxyl substitution degrees and viscosities. Currently HPMC Hydroxy Propyl Methyl Cellulose is one of the most popular pharmaceutical excipients all around the world. It can be used as tablet binder, disintegrating agent, controlled release agent, film-forming agent etc.. Its aqueous solution or alcoholic solution, as the binder, can form a layer of thin film on the particle surface, which can help improving the stability of the medicines. And it is especially good for some unstable medicines. Generally viscosity 5cps can be used for tablet coating, 15cps to 50cps be used as the binder and more than 100cps can be used for controlled releasing. Common concentration of HPMC Hydroxy Propyl Methyl Cellulose for binder should be 2%-5%.

     

    Physicochemical property:

    HPMC is white powder with tasteless, odourless and non-toxic. In human body it has no change and is eliminated from the body completely. It is easily dissoved in water and form a kind of colourless and transparent viscous liquid.

     

    Specification:

    ITEM SPECIFICATION
    60RK 65RK 75RK
    Methoxyl content % 28.0-32.0 27.0-30.0 19.0-24.0
    Hydroxypropyl content % 7.0-12.0 4.0-7.5 4.0-12.0
    Viscosity mpa.s 5,15,50,4000 50,4000 100,4000,15000,100000
    Loss on drying % ≤5.0
    Residue on ignition % ≤1.5
    pH 4.0-8.0
    Heavy metal ppm ≤20
    Arsenic ppm ≤2.0
     

    Production Process:

    The production process of HPMC is like this, purified cotton → add caustic soda → solvent treatment → etherification → water scrubbing → centrifugalization → dry. In food industry, HPMC can be used as thickening agent, stabilizer, emulgator and gelatinizing agent.

     
    Application:

    HPMC, as hydrophilic gel matrix material, is the most popular controlled released preparation now. The matrix will expand with water or digestive juic and then form gel barrier to control the release of medicines. Controlled release tablets with HPMC as the matrix has a simple production technology and it has a very good effect of controlled release for different medicines. Besides, its physical properties has no relationship with PH at a range of physiological condition. So it is a perfect and widely used excipient of controlled release medicine.

     

    Characters:
    • The solution of HPMC can form reversible thermal gel after heating. Formation temperature of gel depends on the relative content of Methoxyl and Hydroxypropyl. The higher the substitution degree, the lower the gelation temperature.
    • HPMC Hydroxy Propyl Methyl Cellulose can lower the surface tension of water to 50~60/10-5N/cm2, but surface tension increases when it was heating, which has an opposite character compared with other surfactant.
    • The molecular of HPMC centers in the interfaces (gas-liquid interface or liquid-solid interface). The concentration in the interfaces is much higher than that internal solution.
    Advantages:

    1. The raw materials imported from America make sure our high quality of HPMC Hydroxy Propyl Methyl Cellulose.

    2. Long term service experiences for some global pharmaceutical companies etc.

    3. Stable supply and could provide prompt shipment at any time.

    4. Professional technical supports and provide a proper and unique solution for our customers.

     

    Storage:

    Keep in a dry container, away from heat and sunshine during the process of delivery and storage.

     

    Packaging: 25kg/drum or according to the requests of the customers.

    Gelatining Agent Hydroxypropyl Methylcellulose Excipient E5 For Tablet Coating

     

    FAQ:
     
    1. What is your payment terms?
    We have T/T, LC, DP, Paypal, Moneygram and many other payment terms. For the first cooperation, we prefer T/T in advance or LC at sight.
    2. Can we get smaller quantity of HPMC?
    Generally our MOQ is 100kg and we can deliver it by sea, by air or courier like FedEx etc.. We always do it according to the requirements of the customers.

    Contact Details
    Shanghai Runkey Biotech Co., Ltd.

    Contact Person: terry

    Send your inquiry directly to us (0 / 3000)

    Contact

    Address: Room 601, Building 62, No. 221, Caiyun Road, Shanghai, 201306, China

    • Tel:86-21-58070171
    • Fax:86-21-58070171
    • Worktime:9:00-18:00
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